CHAPTER 13: PERFECT DEFENSES (Part 1)

Meggs, William Joel, and Carol Svec. The Inflammation Cure. Chicago, Il: Contemporary Books, 2003.

INFLAMMATION: STANDING BETWEEN YOU AND DEATH

Cotran, Ramzi, Vinay Kumar, and Tucker Collins. Pathologic Basis of Disease, Sixth Edition. W.B. Saunders Company, 1999.

Meggs, William Joel, and Carol Svec. The Inflammation Cure. Chicago, Il: Contemporary Books, 2003.

Nathan, Carl. “Points of control in inflammation.” Nature 420 (2002): 846-52.

Thibodeau, Gary A., and Kevin T. Patton. The Human Body in Health and Disease, Third Edition. Mosby, Inc., 2002.

PROVOKING INFLAMMATION

Cotran, Ramzi, Vinay Kumar, and Tucker Collins. Pathologic Basis of Disease, Sixth Edition. W.B. Saunders Company, 1999.

Grimble, R.F. “Dietary Lipids and the Inflammatory Response.” Proceedings of the Nutrition Society 57 (1998): 535-42.

Hansen, Margie. Pathophysiology: Foundations of Disease and Clinical Intervention. W.B. Saunders Company, 1998.

“Inflammation’s Dual Role.” 9 Nov. 2004. 13 Mar. 2008 <http://www.usatoday.com/news/health/2004-11-09-inflammation_x.htm>.

Meggs, William Joel, and Carol Svec. The Inflammation Cure. Chicago, Il: Contemporary Books, 2003.

Thibodeau, Gary A., and Kevin T. Patton. The Human Body in Health and Disease, Third Edition. Mosby, Inc., 2002.

Waugh, Anne, and Allison Grant. Anatomy and Physiology in Health and Illness, Ninth edition. Churchill Livingstone, 2001.

Weiss, Ursula. “Inflammation.” Nature 420 (2002): 846.

World Cancer Research Fund and American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. Rep. Washington DC: AICR, 2007.

INFLAMMATION’S POWER

Bartfai, Tamas. “Telling the brain about pain.” Nature 410 (2001): 425-27.

Cotran, Ramzi, Vinay Kumar, and Tucker Collins. Pathologic Basis of Disease, Sixth Edition. W.B. Saunders Company, 1999.

Fleming, Richard M., and Tom Monte. Stop Inflammation Now. New York: G.P. Putnam’s Sons, 2004.

Hansen, Margie. Pathophysiology: Foundations of Disease and Clinical Intervention. W.B. Saunders Company, 1998.

Horuk, Richard. “Chemokines beyond inflammation.” Nature 393 (1998): 524-25.

“Inflammation’s Dual Role”. 9 Nov. 2004. 13 Mar. 2008 <http://www.usatoday.com/news/health/2004-11-09-inflammation_x.htm>.

LaFee, Scott. “Body Heat.” San Diego Union Tribune 30 Mar. 2005: F1, F4.

Meggs, William Joel, and Carol Svec. The Inflammation Cure. Chicago, Il: Contemporary Books, 2003.

Nathan, Carl. “Points of control in inflammation.” Nature 420 (2002): 846-52.

Pickup, John C. “Inflammation and Activated Innate Immunity in the Pathogenesis of Type 2 Diabetes.” Diabetes Care 27 (2004): 813-23.

Thibodeau, Gary A., and Kevin T. Patton. The Human Body in Health and Disease, Third Edition. Mosby, Inc., 2002.

Tracey, Kevin J. “The inflammatory reflex.” Nature 420 (2002): 853-59.

Vasto, Sonya, et al. “Inflammatory Networks in Ageing, Age-Related Diseases and Longevity.” Mechanisms of Ageing and Development 128 (2007): 83-91.

Waugh, Anne, and Allison Grant. Anatomy and Physiology in Health and Illness, Ninth edition. Churchill Livingstone, 2001.

MEASURING INFLAMMATION: KNOWING WHERE YOU STAND

D’Amore, Paula J. “Evolution of C-Reactive Protein as a Cardiac Risk Factor.” Lab Med 36 (2005): 234-38

Fleming, Richard M., and Tom Monte. Stop Inflammation Now. New York: G.P. Putnam’s Sons, 2004.

Pelsajovich, Andrea, et al. “C-reactive Protein at the Interface Between Innate Immunity and Inflammation.” Expert Rev Clin Immunol 4 (2008): 379-90.

Pickup, John C. “Inflammation and Activated Innate Immunity in the Pathogenesis of Type 2 Diabetes.” Diabetes Care 27 (2004): 813-23.

THE COIN HAS ANOTHER SIDE

Cohen, Jonathan. “The immunopathogenesis of sepsis.” Nature 420 (2002): 885-91.

Cotran, Ramzi, Vinay Kumar, and Tucker Collins. Pathologic Basis of Disease, Sixth Edition. W.B. Saunders Company, 1999.

Pan, Min-Hsiung, et al. “Modulation of Inflammatory Genes by Natural Dietary Bioactive Compounds.” J Agric Food Chem. 57 (2009): 4467-477.

Thibodeau, Gary A., and Kevin T. Patton. The Human Body in Health and Disease, Third Edition. Mosby, Inc., 2002.

Waugh, Anne, and Allison Grant. Anatomy and Physiology in Health and Illness, Ninth edition. Churchill Livingstone, 2001.

Weiss, Ursula. “Inflammation.” Nature 420 (2002): 846.

Vasto, Sonya, et al. “Inflammatory Networks in Ageing, Age-Related Diseases and Longevity.” Mechanisms of Ageing and Development 128 (2007): 83-91.

BALANCE IS EVERYTHING

Barclay, Laurie, and C. Vega. “Withdrawing Aspirin May Significantly Increase Stroke Risk.” 11 Aug. 2005. 14 Aug. 2005 <http://www.medscape.com/viewarticle/510469_print>.

Cotran, Ramzi, Vinay Kumar, and Tucker Collins. Pathologic Basis of Disease, Sixth Edition. W.B. Saunders Company, 1999.

Coussens, Lisa M., and Zena Werb. “Inflammation and cancer.” Nature 420 (2002): 860-67.

Doheny, Kathleen. “Stopping aspirin therapy boost stroke dangers.” 2 Feb. 2005. 3 Feb. 2005 <http://www.forbes.com/lifestyle/health/feeds/hscout/2005/02/02/hscout523777.html>.

Franceschi, Claudio, et al. “Inflammaging and Anti-Inflammaging: A Systemic Perspective on Aging and Longevity Emerged from Studies in Humans.” Mechanisms of Ageing and Development 128 (2007): 92-105.

Nathan, Carl. “Points of control in inflammation.” Nature 420 (2002): 846-52.

“Stopping aspirin heightens risk of new coronary events in heart disease patients.” 2 Feb. 2005. 3 Feb. 2005 <http://www.medscape.com/viewarticle/498669_print>.

Tracey, Kevin J. “The inflammatory reflex.” Nature 420 (2002): 853-59.

IMMUNITY: YOUR “FIRST RESPONDER” POWERHOUSE

“Breaking Down the Immune System.” UCSF Magazine Aug. 2004.

Cox, Christine. “The Immune System: Part I.” Sept. 2005. 27 Sept. 2005 <http://www.nutritionadvocate.com/story/diet_and_immune.html>.

Fleming, Richard M., and Tom Monte. Stop Inflammation Now. New York: G.P. Putnam’s Sons, 2004.

Hansen, Margie. Pathophysiology: Foundations of Disease and Clinical Intervention. W.B. Saunders Company, 1998.

Meggs, William Joel, and Carol Svec. The Inflammation Cure. Chicago, Il: Contemporary Books, 2003.

Thibodeau, Gary A., and Kevin T. Patton. The Human Body in Health and Disease, Third Edition. Mosby, Inc., 2002.

Tracey, Kevin J. “The inflammatory reflex.” Nature 420 (2002): 853-59.

Waugh, Anne, and Allison Grant. Anatomy and Physiology in Health and Illness, Ninth edition. Churchill Livingstone, 2001.

CATALOGUE OF MISERY

Anderson, Pauline. “New Findings Further Explain Strong Link Between Depression, Heart Disease, and Stroke.” 2009. 18 Feb. 2009<http://www.medscape.com/viewarticle/588400_print>.

Barnes, PJ, and B.R. Celli. “Systemic Manifestations and Comorbidities of COPD.” Eur Respir J 33 (2009): 1165-185.

Brown, Anthony J. Elevated CRP Level linked to Age-Related Macular Degeneration. 10 Feb. 2004. 11 Feb. 2004 <http://www.medscape.com/viewarticle/468934_print>.

Cassels, Caroline. “Macular Degeneration Linked to Increased Stroke Risk.” 28 July 2006. 8 Aug. 2006 <http://www.medscape.com/viewarticle/541886_print>.

Cotran, Ramzi, Vinay Kumar, and Tucker Collins. Pathologic Basis of Disease, Sixth Edition. W.B. Saunders Company, 1999.

Coussens, Lisa M., and Zena Werb. “Inflammation and cancer.” Nature 420 (2002): 860-67.

D’Amore, Paula J. “Evolution of C-Reactive Protein as a Cardiac Risk Factor.” Lab Med 36 (2005): 234-38.

De Nardin, E. “The role of inflammatory and immunological mediators in periodontitis and cardiovascular disease.” Ann Periodontol 6 (2001): 30-40.

Douglas, David. “Global Inflammation: a Cardiovascular Risk Marker for Women.” 28 Dec. 2005. 29 Dec. 2005 <http://www.medscape.com/viewarticle/520593_print>.

Eckel, Robert H., Scott M. Grundy, and Paul Z. Zimmet. “The Metabolic Syndrome.” Lancet 365 (2005): 1415-428.

Elenkov, Ilia J., et al. “Cytokine Dysregulation, Inflammation and Well-Being.” Neuroimmunomodulation 12 (2005): 255-69.

Elliott, Victoria Stagg. “Sinusitis guidelines point the way for further research.” Amednews.com. 27 Dec. 2004. <http://www.ama-assn.org/amednews/2004/12/27/hlsb1227.htm>.

Elzirik, Decio L., ML Colli, and F. Ortis. “The Role of Inflammation in Insulitis and B-Cell Loss in Type 1 Diabetes.” 29 May 2009. 11 June 2009<http://www.medscape.com/viewarticle/703547_print>.

Fleming, Richard M., and Tom Monte. Stop Inflammation Now. New York: G.P. Putnam’s Sons, 2004.

Forrester, James S., and Justing Bick-Forrester. “Persistence of Inflammatory Cytokines Cause a Spectrum of Chronic Progressive Diseases: Implications for Therapy.” Med Hypotheses 65 (2005): 227-31.

Glaser, Gabrielle. “Doctors rethinking treatments for sick sinuses.” 17 Dec. 2002. New York Times. 17 Dec. 2002<http://www.nytimes.com/2002/12/17/health/anatomy/17sinu.html>.

Glurich, I., et al. “Systemic Inflammation in Cardiovascular and Periodontal Disease: A Comparative Study.” Clin Diagn Lab Immunol 9 (2002): 425-32.

Golden, Sherita Hill, et al. “Examining a Bidirectional Association Between Depressive Symptoms and Diabetes.” JAMA 299 (2008): 2751-759.

Gorman, Christine, and Alice Park. “The Secret Killer.” Time 23 Feb. 2004: 38-46.

Grady, Denise. “Study Says Test May Surpass Cholesterol as Risk Marker.” New York Times 13 Nov. 2002.

“High C-Reactive Protein Levels Predict Onset of Hypertension.” 9 Dec. 2003. 10 Dec. 2003. http://www.medscape.com/viewarticle/465726_print

Hirschler, Ben. “Childhood Allergy Epidemic on the Rise Worldwide.” 24 Aug. 2006. 29 Aug. 2006 <http://news.yahoo.com/s/nm/20060824/hl_nm/allergies>.

Holgate, Stephen T. “The epidemic of allergy and asthma.” Nature 402 suppl (1999): B2-B4.

Holt, PG, C. Macaubas, PA Stumbles, and PD Sly. “The role of allergy in the development of asthma.” Nature 402 suppl (1999): B12-17.

Iacopino, AM. “Periodontitis and diabetes interrelationships: role of inflammation.” Ann Periodontol 6 (2001): 125-37.

“Inflammation’s Dual Role.” 9 Nov. 2004. 13 Mar. 2008 <http://www.usatoday.com/news/health/2004-11-09-inflammation_x.htm>.

Kushner, Irving, Debra Rzewnicki, and David Samols. “What Does Minor Elevation of C-Reactive Protein Signify?” Am J Med 119 (2006): 166.e17-66.e28.

LaFee, Scott. “Body Heat.” San Diego Union Tribune 30 Mar. 2005: F1, F4.

Leonard, Brian E. “Changes in the Immune System in Depression and Dementia: Causal or Co-incidental Effects?” Int J Devl Neuroscience 19 (2001): 305-12.

Ludwig, RJ, et al. “Psoriasis: A Possible Risk Factor for Development of Coronary Artery Calcification.” Br J Dermatol 156 (2007): 271-76.

Malemud, Charles J., and Mark E. Schulte. “Is There a Final Common Pathway for Arthritis?” Future Rheumatol 3 (2008): 253-68.

Mangiafico, Roberto A., et al. “Impaired Cognitive Performance in Asymptomatic Peripheral Arterial Disease: Relation to C-Reactive Protein and D-dimer Levels.” Age and Ageing 35 (2006): 60-65.

Masters, Coco. “Ahead of Their Time.” Time 13 Nov. 2006: 168.

Meggs, William Joel, and Carol Svec. The Inflammation Cure. Chicago, Il: Contemporary Books, 2003.

Meyer, Michele. “Inflammation Emerges as a Marker to Detect Heart Attack Risk.” AARP Bulletin Online Oct. 2003.<http://www.aarp.org/bulletin/yourhealth/articles/a2003-10-15-revelations.html>.

Morris, Martha Clare. “Diet and Alzheimer’s Disease: What the Evidence Shows.” 2004. 24 Dec. 2004 <http://www.medscape.com/viewarticle/466037_print>.

Neergaard, Lauran. “Report: 1 in 8 Babies Born Premature.” 14 July 2006. 15 July 2006 <http://news.yahoo.com/s/ap/20060715/ap_on_he_me/premature_births>.

Pai, Jennifer K., et al. “Inflammatory Markers and the Risk of Coronary Heart Disease in Men and Women.” N Engl J Med 351 (2004): 2599-610.

Pickup, John C. “Inflammation and Activated Innate Immunity in the Pathogenesis of Type 2 Diabetes.” Diabetes Care 27 (2004): 813-23.

Pietropaolo, Massimo, et al. “The Heterogeneity of Diabetes: Unraveling a Dispute: Is Systemic Inflammation Related to Islet Autoimmunity.” Diabetes 56 (2007): 1189-197.

“Proteins Hold Clues to Chronic Pain.” 26 July 2006. 26 July 2006 <http://news.yahoo.com/s/hsn/20060726/hl_hsn/proteinsholdcluestochronicpain>.

Roan, Shari. “Survival, At a Cost.” Los Angeles Times 21 Nov. 2005.

Romero, Roberto, et al. “The Role of Inflammation and Infection in Preterm Birth.” Semin Liver Dis 25 (2007): 21-39.

Sandek, Anja, et al. “The Emerging Role of the Gut in Chronic Heart Failure.” Curr Opin Clin Nutr Metab Care 11 (2008): 632-39.

Sevenoaks, Martin J., and Robert A. Stockley. “Chronic Obstructive Pulmonary Disease, Inflammation and Co-Morbidity – A Common Inflammatory Phenotype.” Respiratory Research 7 (2006): 70.

Snyder, Ursula. “Preterm Birth as a Social Disease.” 6 July 2004. 13 July 2004 <http://www.medscape.com/viewarticle/481732?src=mp>.

Stein, Rob. “Body’s First Defense May be Root of Diseases.” Washington Post 16 Feb. 2003: A01.

Thibodeau, Gary A., and Kevin T. Patton. The Human Body in Health and Disease, Third Edition. Mosby, Inc., 2002.

Vasto, Sonya, et al. “Inflammatory Networks in Ageing, Age-Related Diseases and Longevity.” Mechanisms of Ageing and Development 128 (2007): 83-91.

Weil, Andrew. “The Truth About Inflammation.” Dr. Andrew Weil’s Self Healing Nov. 2004: 4-5.

Weiner, Howard L., and Dennis J. Selkoe. “Inflammation and therapeutic vaccination in CNS diseases.” Nature 420 (2002): 879-84.

World Cancer Research Fund and American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. Rep. Washington DC: AICR, 2007.

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